We stayed at the Karma Sanctum Soho for two nights while on a weekend trip to London. The hotel is located in the most perfect location, right next to Regent and Oxford Street, perfect for shopping. And walking distance to Buckingham Palace, Westminister and a bunch of food places in Soho.
We came there quite early, but were able to check-in early, which was great!
We only spend time there when we were going to bed, so we didn't experience the hotel. We knew there was a restaurant and a bar there, but we didn't try them out.
The hotels atmosphere is dark and mysterious. I would say it's perfect for couples who are on a weekend trip to London. The room was quite small, but good enough for us.
We only had an issue with the door to the bathroom was difficult to close, and that someone check-in to our room while we were getting ready to leave before checking-out.
Still, great hotel in general!